Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL789680 | 0.98 | FGFR1 (0.55) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL29533362 | 0.84 | KMT2A (0.64) | KMT2ANPC1MEN1RAB9ATLR9 | |
| SCHEMBL8574353 | 0.83 | KMT2A (0.74) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL22919305 | 0.83 | PSMB5 (0.71) | KMT2ANPC1MEN1RAB9ATLR9 | |
| SCHEMBL790060 | 0.83 | FGFR1 (0.54) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL789883 | 0.79 | MAP4K4 (0.54) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL28457308 | 0.79 | KMT2A (0.51) | KMT2ANPC1MEN1RAB9ATLR9 | |
| SCHEMBL10277962 | 0.78 | HSD17B1 (0.51) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL28156921 | 0.76 | FGFR1 (0.62) | FGFR1SRCKMT2ANPC1MEN1 | |
| SCHEMBL807058 | 0.76 | MEN1 (0.48) | FGFR1SRCKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |