Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 9/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29533241 | 0.99 | BTK (0.51) | BTKLCKGSK3BMAPK14ABL1 | |
| Hydrochloric Acid SCHEMBL22659441 | 0.99 | BTK (0.51) | BTKLCKGSK3BMAPK14ABL1 | |
| SCHEMBL22659931 | 0.92 | BTK (0.46) | BTKLCKGSK3BMAPK14 | |
| SCHEMBL29533570 | 0.92 | BTK (0.46) | BTKLCKGSK3BMAPK14 | |
| SCHEMBL22659580 | 0.91 | BTK (0.51) | BTKLCKGSK3B | |
| SCHEMBL29532906 | 0.91 | BTK (0.51) | BTKLCKGSK3B | |
| SCHEMBL29532936 | 0.89 | BTK (0.55) | BTKLCKGSK3BMAPK14ABL1 | |
| SCHEMBL22659505 | 0.89 | BTK (0.55) | BTKLCKGSK3BMAPK14ABL1 | |
| SCHEMBL22659808 | 0.89 | BTK (0.53) | BTKLCKGSK3BMAPK14ABL1 | |
| SCHEMBL29533525 | 0.89 | BTK (0.53) | BTKLCKGSK3BMAPK14ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232330-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2020-11-19 | — | — | WO | disclosed |