Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393876 | 1.00 | PMP22 (0.43) | PMP22NOS3NOS1NOS2GSR | |
| Tilarginine SCHEMBL6370536 | 0.89 | OTC (0.51) | PMP22NOS3NOS1NOS2GSR | |
| Tilarginine SCHEMBL12028766 | 0.89 | OTC (0.51) | PMP22NOS3NOS1NOS2GSR | |
| Tilarginine SCHEMBL315843 | 0.89 | OTC (0.51) | PMP22NOS3NOS1NOS2GSR | |
| SCHEMBL1006081 | 0.88 | GSR (0.47) | NOS3NOS1NOS2GSRCYP1A2 | |
| Tilarginine SCHEMBL2229626 | 0.88 | OTC (0.50) | PMP22NOS3NOS1NOS2GSR | |
| SCHEMBL14423587 | 0.88 | GSR (0.47) | NOS3NOS1NOS2GSRCYP1A2 | |
| Tilarginine SCHEMBL1321022 | 0.86 | OTC (0.49) | PMP22NOS3NOS1NOS2GSR | |
| SCHEMBL1344672 | 0.84 | SLC1A2 (0.42) | PMP22NOS3NOS1NOS2GSR | |
| Nor-Noha SCHEMBL4097591 | 0.83 | GSR (0.42) | PMP22NOS3NOS1NOS2GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348476-A | Peptide-based linkers | 拜斯科技术开发有限公司 | 2023-06-27 | — | — | CN | claimed |
| EP-4188938-A1 | PEPTIDE-BASED LINKERS | BicycleTX Limited (GB) | 2023-06-07 | — | — | EP | claimed |
| WO-2022029420-A1 | PEPTIDE-BASED LINKERS | BICYCLETX LIMITED (GB) | 2022-02-10 | — | — | WO | claimed |
| CN-116348476-A | Peptide-based linkers | 拜斯科技术开发有限公司 | 2023-06-27 | — | — | CN | disclosed |