Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 9/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660085 | 1.00 | BTK (0.50) | BTKLCKGSK3BPIK3C3MAPK14 | |
| SCHEMBL22659422 | 0.94 | BTK (0.55) | BTKLCKGSK3BMAPK14 | |
| SCHEMBL29533386 | 0.94 | BTK (0.55) | BTKLCKGSK3BMAPK14 | |
| SCHEMBL22659668 | 0.91 | BTK (0.50) | BTKLCKGSK3BPIK3C3MAPK14 | |
| SCHEMBL29533262 | 0.91 | BTK (0.50) | BTKLCKGSK3BPIK3C3MAPK14 | |
| SCHEMBL22664661 | 0.91 | BTK (0.54) | BTKLCKGSK3BMAPK14 | |
| SCHEMBL22659699 | 0.91 | BTK (0.54) | BTKLCKGSK3BPIK3C3 | |
| SCHEMBL29532904 | 0.91 | BTK (0.54) | BTKLCKGSK3BPIK3C3 | |
| Hydrochloric Acid SCHEMBL22659335 | 0.91 | BTK (0.53) | BTKLCKGSK3BMAPK14 | |
| Hydrochloric Acid SCHEMBL29533253 | 0.91 | BTK (0.53) | BTKLCKGSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3969124-A1 | INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-03-23 | — | — | EP | disclosed |