Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240998 | 1.00 | PTK2 (0.54) | PTK2TDP1MEN1KMT2ACA1 | |
| SCHEMBL15337919 | 0.85 | PTK2 (0.38) | PTK2CA1CA2CA9CA12 | |
| SCHEMBL10027390 | 0.83 | PTK2 (0.43) | PTK2TDP1MEN1KMT2ACA1 | |
| SCHEMBL30391007 | 0.77 | PTK2 (0.39) | PTK2CA1CA2CA9ALDH1A1 | |
| SCHEMBL2264764 | 0.77 | GAA (0.53) | PTK2TDP1CA1CA2CA9 | |
| SCHEMBL23041366 | 0.77 | CD44 (0.48) | PTK2TDP1CYP3A4ALOX15SMN1; SMN2 | |
| SCHEMBL19884912 | 0.77 | PTK2 (0.39) | PTK2CA1CA2CA9ALDH1A1 | |
| SCHEMBL17298240 | 0.77 | CYP3A4 (0.55) | TDP1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL30490095 | 0.77 | GAA (0.53) | PTK2TDP1CA1CA2CA9 | |
| SCHEMBL19692692 | 0.72 | PTK2 (0.33) | PTK2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380700-A | Non-platinum based anti-cancer compounds for targeted chemotherapy | 卢庆彬 | 2022-04-22 | — | — | CN | disclosed |