Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19884912 | 1.00 | PTK2 (0.39) | PTK2ALDH1A1CA1CA2CA3 | |
| SCHEMBL28566129 | 0.86 | ALDH1A1 (0.40) | PTK2ALDH1A1CA1CA2CA3 | |
| SCHEMBL219912 | 0.86 | ALDH1A1 (0.40) | PTK2ALDH1A1CA1CA2CA3 | |
| SCHEMBL27728516 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL21834387 | 0.79 | ALDH1A1 (0.35) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL26512765 | 0.79 | CYP3A4 (0.46) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL27728509 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL21834381 | 0.79 | GAA (0.50) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL15575436 | 0.79 | CYP3A4 (0.46) | ALDH1A1CA1CA2CA3CA9 | |
| SCHEMBL14129494 | 0.77 | CA1 (0.32) | CA1CA2CA3CA9HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-4161656-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | Kinnate Biopharma Inc. (US) | 2023-04-12 | — | — | EP | disclosed |