Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.37 |
| ▸ | CD69 | Q07108 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535351 | 1.00 | MAPK1 (0.53) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL19521448 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL29535436 | 0.90 | MAPK1 (0.62) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL30694316 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL30694301 | 0.90 | MAPK1 (0.62) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL23631136 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL4258624 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL4322755 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL21067800 | 0.90 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBNOD2 | |
| SCHEMBL26597373 | 0.90 | MAPK1 (0.62) | MAPK1LGALS3ALDH1A1THRBNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366853-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12090261-B2 | Method for modulating endothelial glycocalyx structure | EXTHERA MEDICAL CORPORATION (US) | 2024-09-17 | — | — | US | disclosed |
| EP-3969014-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | ExThera Medical Corporation (US) | 2022-03-23 | — | — | EP | disclosed |