Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LGALS3 | P17931 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23631136 | 1.00 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL21067800 | 1.00 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL4258624 | 1.00 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL4322755 | 1.00 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL30694316 | 1.00 | MAPK1 (0.52) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL30089312 | 0.91 | LGALS3 (0.54) | MAPK1LGALS3ALDH1A1THRBLGALS8 | |
| SCHEMBL29535303 | 0.90 | MAPK1 (0.53) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL29535351 | 0.90 | MAPK1 (0.53) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL30694301 | 0.89 | MAPK1 (0.62) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL29535436 | 0.89 | MAPK1 (0.62) | MAPK1LGALS3ALDH1A1THRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656735-A1 | INIBHITION OF REVERSE TRANSCRIPTION DERIVED FROM RIBOSOMAL RNA | Toyobo Co., Ltd. (JP) | 2025-12-03 | — | — | EP | disclosed |
| EP-4570825-A2 | THE IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT | Inovio Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-3448993-B1 | THE IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT | INOVIO PHARMACEUTICALS INC (US) | 2025-04-30 | — | — | EP | disclosed |
| US-20240366853-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12090261-B2 | Method for modulating endothelial glycocalyx structure | EXTHERA MEDICAL CORPORATION (US) | 2024-09-17 | — | — | US | disclosed |
| US-20230092556-A1 | IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT | INOVIO PHARMACEUTICALS INC (US) | 2023-03-23 | — | — | US | disclosed |
| EP-3969014-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | ExThera Medical Corporation (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20190284263-A1 | IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT | INOVIO PHARMACEUTICALS, INC. (US) | 2019-09-19 | — | — | US | disclosed |
| WO-2017190147-A1 | THE IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT | INOVIO PHARMACEUTICALS, INC. (US) | 2017-11-02 | — | — | WO | disclosed |