Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.65 |
| ▸ | EGFR | P00533 | 11/20 | 0.65 |
| ▸ | SRC | P12931 | 8/20 | 0.65 |
| ▸ | BMX | P51813 | 1/20 | 0.65 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568473 | 0.97 | BTK (0.66) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL28567975 | 0.87 | BTK (0.64) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL28574332 | 0.86 | BTK (0.69) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL28568488 | 0.85 | BTK (0.66) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15670197 | 0.85 | BTK (0.69) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15669389 | 0.85 | BTK (0.69) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL15669390 | 0.85 | BTK (0.69) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL19636166 | 0.83 | BTK (0.82) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL19635984 | 0.82 | BTK (0.91) | BTKEGFRSRCBMXNR4A3 | |
| SCHEMBL28568472 | 0.81 | BTK (0.49) | BTKEGFRSRCBMXNR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812100-B | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2022-04-05 | — | — | CN | disclosed |