Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.77 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | YES1 | P07947 | 1/20 | 0.68 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28574338 | 0.96 | BTK (0.71) | BTKLCKYES1PTK6 | |
| SCHEMBL29536399 | 0.93 | BTK (0.78) | BTKLCKYES1PTK6 | |
| SCHEMBL28575347 | 0.92 | BTK (0.68) | BTKLCKYES1PTK6 | |
| SCHEMBL29536062 | 0.92 | BTK (0.68) | BTKLCKYES1PTK6 | |
| SCHEMBL24734971 | 0.92 | BTK (0.87) | BTKLCKYES1PTK6 | |
| SCHEMBL29536272 | 0.92 | BTK (0.87) | BTKLCKYES1PTK6 | |
| Hydrochloric Acid SCHEMBL29106909 | 0.91 | BTK (0.85) | BTKLCKYES1PTK6 | |
| Hydrochloric Acid SCHEMBL29841443 | 0.91 | BTK (0.85) | BTKLCKYES1PTK6 | |
| SCHEMBL29536988 | 0.90 | BTK (0.74) | BTK | |
| Trifluoroacetic Acid SCHEMBL28577105 | 0.89 | BTK (0.70) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812100-B | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2022-04-05 | — | — | CN | disclosed |