Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462768 | 0.92 | L3MBTL1 (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL29768150 | 0.89 | HCRTR1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL2570484 | 0.85 | TP53 (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2570483 | 0.85 | TP53 (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18689125 | 0.85 | TP53 (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL3493185 | 0.82 | CA1 (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2546757 | 0.79 | POLB (0.41) | DPP4PREPFAP | |
| SCHEMBL2788731 | 0.79 | POLB (0.41) | DPP4PREPFAP | |
| SCHEMBL793131 | 0.79 | POLB (0.41) | DPP4PREPFAP | |
| SCHEMBL345455 | 0.77 | KDM4E (0.30) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220257774-A1 | AROMATIC AMINE AR AHD BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | HINOVA PHARMACEUTICALS INC. (CN) | 2022-08-18 | — | — | US | disclosed |
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257774-A1 | AROMATIC AMINE AR AHD BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | AR, BRD4, BRDT | KDM4E 35/4885USP2 1066/4885ALDH1A1 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.