Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537219 | 0.85 | MAPK14 (0.32) | L3MBTL1KDM4EALDH1A1NPSR1MAPK14 | |
| SCHEMBL26077874 | 0.82 | MAPK8 (0.33) | KDM4EALDH1A1NPSR1MAPK14MAP4K4 | |
| SCHEMBL25420591 | 0.80 | MET (0.35) | MAPK14TRPA1PTGS2 | |
| SCHEMBL29537104 | 0.80 | MET (0.35) | MAPK14TRPA1PTGS2 | |
| SCHEMBL30595879 | 0.80 | SYK (0.44) | — | |
| SCHEMBL26075403 | 0.80 | SYK (0.44) | — | |
| SCHEMBL25421846 | 0.79 | BRD4 (0.46) | MAPK14PTGS2 | |
| SCHEMBL29536472 | 0.79 | BRD4 (0.46) | MAPK14PTGS2 | |
| SCHEMBL30595902 | 0.78 | MAPK8 (0.41) | MAPK14 | |
| SCHEMBL26075404 | 0.78 | MAPK8 (0.41) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |