Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25223077 | 1.00 | CCNA2 (0.40) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL27103103 | 0.77 | FLT3 (0.39) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL30595898 | 0.73 | PIK3CA (0.36) | MAPK1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL25230887 | 0.73 | PIK3CA (0.36) | MAPK1GAAPOLBKDM4EALDH1A1 | |
| SCHEMBL25230025 | 0.73 | FLT3 (0.40) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL29536830 | 0.73 | FLT3 (0.40) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL25225986 | 0.67 | FLT3 (0.39) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL30595895 | 0.67 | FLT3 (0.39) | CCNA2CDK2CCNA1MAPK1KMT2A | |
| SCHEMBL27103106 | 0.65 | PRKCH (0.35) | EGFRPRKCHPRKCEPRKCQPRKCD | |
| SCHEMBL25420854 | 0.64 | KDM4E (0.41) | MAPK1GAAPOLBEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |