Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230025 | 1.00 | FLT3 (0.40) | FLT3CCNA2CDK2CCNA1EGFR | |
| SCHEMBL27103103 | 0.76 | FLT3 (0.39) | FLT3CCNA2CDK2CCNA1EGFR | |
| SCHEMBL30595895 | 0.76 | FLT3 (0.39) | FLT3CCNA2CDK2CCNA1EGFR | |
| SCHEMBL25225986 | 0.76 | FLT3 (0.39) | FLT3CCNA2CDK2CCNA1EGFR | |
| SCHEMBL30595901 | 0.74 | ROCK1 (0.32) | — | |
| SCHEMBL25269634 | 0.74 | ROCK1 (0.32) | — | |
| SCHEMBL25223077 | 0.73 | CCNA2 (0.40) | CCNA2CDK2CCNA1EGFRPOLB | |
| SCHEMBL29537006 | 0.73 | CCNA2 (0.40) | CCNA2CDK2CCNA1EGFRPOLB | |
| SCHEMBL25221516 | 0.66 | KDM4E (0.51) | FLT3CDK2POLBKMT2AMAPK1 | |
| SCHEMBL29313773 | 0.66 | CCNA2 (0.46) | FLT3CCNA2CDK2CCNA1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |