Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20264635 | 0.84 | DYRK1A (0.55) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL27955921 | 0.83 | DYRK1A (0.37) | KMT2AMEN1ALDH1A1HPGDPARP1 | |
| SCHEMBL4048366 | 0.82 | L3MBTL1 (0.39) | KMT2AMEN1ALDH1A1PARP1DYRK1A | |
| SCHEMBL11165545 | 0.78 | PARP1 (0.53) | PARP1KDM4E | |
| SCHEMBL1970017 | 0.76 | HTT (0.45) | KMT2AMEN1ALDH1A1CES2SMN1; SMN2 | |
| SCHEMBL574325 | 0.73 | TTK (0.44) | KMT2AMEN1ALDH1A1HPGDPARP1 | |
| SCHEMBL18696150 | 0.73 | CDC7 (0.43) | KMT2AMEN1ALDH1A1PARP1CYP1A2 | |
| SCHEMBL1000301 | 0.73 | DAO (0.50) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL16918372 | 0.72 | DAO (0.53) | ALDH1A1PARP1DYRK1AATMKDM4E | |
| SCHEMBL21086635 | 0.72 | DYRK1A (0.40) | ALDH1A1PARP1DYRK1AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |