Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.34 |
| ▸ | AKT2 | P31751 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 2/20 | 0.30 |
| ▸ | PDE6A | P16499 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271264 | 1.00 | AKT1 (0.34) | AKT1AKT2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25227024 | 0.82 | AKT1 (0.39) | AKT1AKT2ALDH1A1HTTMAPT | |
| SCHEMBL29536669 | 0.82 | AKT1 (0.39) | AKT1AKT2ALDH1A1HTTMAPT | |
| SCHEMBL29536658 | 0.81 | AKT1 (0.39) | AKT1AKT2ALDH1A1HTT | |
| SCHEMBL25271560 | 0.81 | AKT1 (0.39) | AKT1AKT2ALDH1A1HTT | |
| SCHEMBL25278070 | 0.81 | CYP1A2 (0.40) | AKT1AKT2ALDH1A1HTTMAPT | |
| SCHEMBL29536592 | 0.80 | CDK1 (0.39) | AKT1AKT2 | |
| SCHEMBL25227902 | 0.80 | CDK1 (0.39) | AKT1AKT2 | |
| SCHEMBL25227955 | 0.80 | CDK1 (0.39) | AKT1AKT2 | |
| SCHEMBL24271449 | 0.78 | AKT1 (0.34) | AKT1AKT2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |