Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 5/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL25423226 | 1.00 | MAPK8 (0.38) | MAPK8STAT6JAK3CCNT1CCNE1 | |
| Formic Acid SCHEMBL25423830 | 0.92 | SCN9A (0.39) | CCNT1CCNE1CDK2CDK9EGFR | |
| Formic Acid SCHEMBL29536657 | 0.92 | SCN9A (0.39) | CCNT1CCNE1CDK2CDK9EGFR | |
| Formic Acid SCHEMBL30595871 | 0.87 | EGFR (0.43) | JAK3CDK2EGFRBTK | |
| SCHEMBL30595902 | 0.85 | MAPK8 (0.41) | MAPK8JAK3CCNT1CCNE1CDK2 | |
| SCHEMBL26075404 | 0.85 | MAPK8 (0.41) | MAPK8JAK3CCNT1CCNE1CDK2 | |
| SCHEMBL26076556 | 0.84 | EGFR (0.45) | JAK3CDK2EGFRBTK | |
| SCHEMBL30590717 | 0.84 | EGFR (0.45) | JAK3CDK2EGFRBTK | |
| Formic Acid SCHEMBL30595851 | 0.82 | EGFR (0.48) | JAK3EGFRBTK | |
| SCHEMBL30590720 | 0.80 | EGFR (0.50) | JAK3EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |