Formic Acid

SCHEMBL25423830

C=C(C(N)=O)c1cccc(Nc2ncc3c(n2)N2CCN=C2C(Oc2ccc(F)cc2F)=C3)c1.O=CO

nearest known ligand 0.39

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	SCN9A	Q15858	4/20	0.39

▸	CCNT1	O60563	2/20	0.39

▸	CCNE1	P24864	2/20	0.39

▸	CDK2	P24941	2/20	0.39

▸	CDK9	P50750	2/20	0.39

▸	SYK	P43405	1/20	0.36

▸	BTK	Q06187	1/20	0.36

▸	MAP3K7	O43318	3/20	0.36

▸	IRAK4	Q9NWZ3	3/20	0.36

▸	EGFR	P00533	3/20	0.35

▸	MET	P08581	1/20	0.35

▸	KDR	P35968	1/20	0.35

▸	NTRK1	P04629	4/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Formic Acid SCHEMBL29536657	1.00	SCN9A (0.39)	SCN9ACCNT1CCNE1CDK2CDK9
Formic Acid SCHEMBL25423226	0.92	MAPK8 (0.38)	SCN9ACCNT1CCNE1CDK2CDK9
Formic Acid SCHEMBL29537715	0.92	MAPK8 (0.38)	SCN9ACCNT1CCNE1CDK2CDK9
Formic Acid SCHEMBL30595851	0.86	EGFR (0.48)	BTKEGFR
SCHEMBL30595879	0.84	SYK (0.44)	SCN9ACCNT1CCNE1CDK2CDK9
SCHEMBL26075403	0.84	SYK (0.44)	SCN9ACCNT1CCNE1CDK2CDK9
SCHEMBL26074894	0.84	EGFR (0.50)	BTKEGFR
SCHEMBL30590720	0.84	EGFR (0.50)	BTKEGFR
Formic Acid SCHEMBL30595871	0.82	EGFR (0.43)	CDK2BTKEGFR
SCHEMBL25421662	0.80	MET (0.45)	CCNT1CCNE1CDK2CDK9EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4192582-A1	KINASE INHIBITORS AND USES THEREOF	ABM Therapeutics Corporation (US)	2023-06-14	—	—	EP	disclosed