Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 3/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.47 |
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27702405 | 0.86 | DDB1 (0.61) | DDB1CRBNHPGDSUSP30NAMPT | |
| SCHEMBL20281909 | 0.80 | PDE4B (0.54) | DDB1CRBNHPGDSUSP30NAMPT | |
| SCHEMBL22608993 | 0.80 | PDE4B (0.54) | DDB1CRBNHPGDSUSP30NAMPT | |
| SCHEMBL665957 | 0.80 | DDB1 (0.57) | DDB1CRBNNAMPTWNT3AJAK2 | |
| SCHEMBL23951735 | 0.80 | TP53 (0.59) | HPGDSUSP30NAMPTPDE4BJAK2 | |
| SCHEMBL697513 | 0.80 | TP53 (0.59) | HPGDSUSP30NAMPTPDE4BJAK2 | |
| SCHEMBL1751432 | 0.80 | TP53 (0.59) | HPGDSUSP30NAMPTPDE4BJAK2 | |
| SCHEMBL1989165 | 0.80 | NAMPT (0.65) | USP30NAMPTPDE4BTP53GPR119 | |
| SCHEMBL1989164 | 0.80 | NAMPT (0.65) | USP30NAMPTPDE4BTP53GPR119 | |
| SCHEMBL610356 | 0.79 | PDE4B (0.53) | DDB1CRBNHPGDSUSP30NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187490-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2022-04-06 | — | — | EP | disclosed |