Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990262 | 1.00 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL1990261 | 1.00 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL6697932 | 0.95 | POLB (0.69) | POLBHTR6LTA4H | |
| SCHEMBL27639459 | 0.82 | — | — | |
| SCHEMBL18577442 | 0.81 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL1443794 | 0.81 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL10132295 | 0.81 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL19654759 | 0.81 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL1673353 | 0.81 | POLB (0.61) | POLBHTR6LTA4H | |
| SCHEMBL10132251 | 0.81 | POLB (0.61) | POLBHTR6LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187490-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2022-04-06 | — | — | EP | disclosed |