Ovemotide

Ovemotide

SCHEMBL29538753

CC(C)CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)C(C)C)C(C)O)C(C)C

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 5/20 0.56
▸ SLC6A2 P23975 2/20 0.55
▸ RAMP1 O60894 1/20 0.53
▸ REN P00797 1/20 0.49
▸ NTSR2 O95665 3/20 0.48
▸ NTSR1 P30989 3/20 0.48
▸ SORT1 Q99523 1/20 0.48
▸ KEAP1 Q14145 1/20 0.48
▸ OPRD1 P41143 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ovemotide SCHEMBL29413273 1.00 CALCRL (0.56) CALCRLSLC6A2RAMP1RENNTSR2
SCHEMBL29449529 0.96 CALCRL (0.56) CALCRLSLC6A2RAMP1RENOPRD1
SCHEMBL30974436 0.92 CALCRL (0.52) CALCRLSLC6A2NTSR2NTSR1OPRD1
SCHEMBL29530922 0.88 SLC6A2 (0.64) CALCRLSLC6A2NTSR2NTSR1OPRD1
SCHEMBL31575684 0.86 KDM1A (0.56) SLC6A2NTSR2NTSR1KEAP1
SCHEMBL29531376 0.85 SLC6A2 (0.72) CALCRLSLC6A2OPRD1
SCHEMBL29530548 0.85 SLC6A2 (0.72) CALCRLSLC6A2OPRD1
SCHEMBL30792437 0.84 NMUR2 (0.56) —
SCHEMBL31410876 0.83 CALCRL (0.49) CALCRLSLC6A2RAMP1NTSR2NTSR1
SCHEMBL29531383 0.81 SLC6A2 (0.71) CALCRLSLC6A2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646428-A1 METHODS AND COMPOSITIONS FOR GENE TRANSDUCTION AND TO CONTROL THE ACTIVITY OF SYNTHETIC AND IMMUNE RECEPTORS Angeles Therapeutics, Inc. (US) 2025-11-12 — — EP disclosed
WO-2024148337-A1 METHODS AND COMPOSITIONS FOR GENE TRANSDUCTION AND TO CONTROL THE ACTIVITY OF SYNTHETIC AND IMMUNE RECEPTORS ANGELES THERAPEUTICS, INC. (US) 2024-07-11 — — WO disclosed
US-20230391846-A1 MODIFIED SOLUBLE T CELL RECEPTOR WuXi Biologics Ireland Limited (IE) 2023-12-07 — — US disclosed
EP-4237437-A1 MODIFIED SOLUBLE T CELL RECEPTOR Wuxi Biologics Ireland Limited (IE) 2023-09-06 — — EP disclosed
CN-116457374-A Modified soluble T cell receptor 上海药明生物技术有限公司 2023-07-18 — — CN disclosed
WO-2022089569-A1 MODIFIED SOLUBLE T CELL RECEPTOR WUXI BIOLOGICS (SHANGHAI) CO., LTD. (CN) 2022-05-05 — — WO disclosed
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