SCHEMBL29449529

SCHEMBL29449529

CC(C)CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NCC(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C)C(=O)O)C(C)O)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 6/20 0.56
▸ RAMP1 O60894 1/20 0.55
▸ SLC6A2 P23975 2/20 0.54
▸ FCGRT P55899 2/20 0.50
▸ OPRM1 P35372 2/20 0.49
▸ OPRD1 P41143 2/20 0.49
▸ OPRK1 P41145 2/20 0.49
▸ REN P00797 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ovemotide SCHEMBL29413273 0.96 CALCRL (0.56) CALCRLRAMP1SLC6A2OPRD1REN
Ovemotide SCHEMBL29538753 0.96 CALCRL (0.56) CALCRLRAMP1SLC6A2OPRD1REN
SCHEMBL30974436 0.88 CALCRL (0.52) CALCRLSLC6A2OPRM1OPRD1
SCHEMBL29530922 0.85 SLC6A2 (0.64) CALCRLSLC6A2OPRM1OPRD1
SCHEMBL31575684 0.83 KDM1A (0.56) SLC6A2
SCHEMBL29657990 0.83 SLC6A2 (0.59) CALCRLSLC6A2OPRM1OPRD1OPRK1
SCHEMBL30792437 0.83 NMUR2 (0.56) —
SCHEMBL29530548 0.83 SLC6A2 (0.72) CALCRLSLC6A2OPRM1OPRD1
SCHEMBL29531376 0.83 SLC6A2 (0.72) CALCRLSLC6A2OPRM1OPRD1
SCHEMBL29657973 0.82 SLC6A2 (0.60) CALCRLSLC6A2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110651189-B Peptide vaccine 特雷斯生物有限公司 2024-10-25 — — CN disclosed
CN-109843929-B Proteolytically cleavable chimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2024-07-05 — — CN disclosed
CN-108430497-B Sugar-targeted therapeutic agents 洛桑聚合联合学院 2024-05-07 — — CN disclosed
CN-110651188-B Population-based immunogenic peptide identification platform 特雷斯生物有限公司 2024-02-02 — — CN disclosed
CN-111150841-B Active immune regulation particle and preparation method and application thereof 优锐生物医药科技(深圳)有限公司 2023-08-15 — — CN disclosed
CN-114605547-A Affinity entities with TCR-like antibody binding domains and uses thereof 阿迪塞特生物公司 2022-06-10 — — CN disclosed
CN-114437217-A Affinity entities with TCR-like antibody binding domains and uses thereof 阿迪塞特生物公司 2022-05-06 — — CN disclosed
CN-108025045-B Affinity entities for TCR-like antibody binding domains with high affinity and excellent specificity and uses thereof 阿迪塞特生物公司 2022-04-26 — — CN disclosed
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