Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 4/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22292200 | 0.99 | USP2 (0.55) | USP2MEN1BLMKMT2APOLB | |
| Hydrochloric Acid SCHEMBL29557664 | 0.97 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL14667860 | 0.96 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL18350813 | 0.96 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL13428258 | 0.96 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL10124264 | 0.94 | USP2 (0.56) | USP2MEN1BLMKMT2APOLB | |
| Perchlorate SCHEMBL29352706 | 0.93 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL18888026 | 0.93 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL17693120 | 0.92 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB | |
| SCHEMBL17693127 | 0.92 | USP2 (0.53) | USP2MEN1BLMKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119331601-A | Preparation and application methods of room-temperature phosphorescent material based on octatomic cucurbituril and 6-bromoisoquinoline derivatives | 贵州大学 | 2025-01-21 | — | — | CN | claimed |
| CN-117092049-A | Method for rapidly detecting rhenium content in ammonium rhenate extraction process | 龙岩市宇恒环保科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-114397284-A | Method for determining activity of serum catalase based on butyl rhodamine B fluorescence quenching method | 甘肃医学院 | 2022-04-26 | — | — | CN | claimed |
| CN-119331601-A | Preparation and application methods of room-temperature phosphorescent material based on octatomic cucurbituril and 6-bromoisoquinoline derivatives | 贵州大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-116139704-B | Light-driven self-cleaning composite filter membrane and preparation method and application thereof | 武汉理工大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-117821781-A | Method for extracting and separating gallium from brown fused alumina smoke dust and application thereof | 武汉科技大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117092049-A | Method for rapidly detecting rhenium content in ammonium rhenate extraction process | 龙岩市宇恒环保科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117092049-A | Method for rapidly detecting rhenium content in ammonium rhenate extraction process | 龙岩市宇恒环保科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116139704-A | Light-driven self-cleaning composite filter membrane and preparation method and application thereof | 武汉理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115178101-A | GO/SiO with ultra-high water flux 2 Composite filter membrane and preparation method thereof | 武汉理工大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-114397284-A | Method for determining activity of serum catalase based on butyl rhodamine B fluorescence quenching method | 甘肃医学院 | 2022-04-26 | — | — | CN | disclosed |
| CN-114397284-A | Method for determining activity of serum catalase based on butyl rhodamine B fluorescence quenching method | 甘肃医学院 | 2022-04-26 | — | — | CN | disclosed |
| CN-114397284-A | Method for determining activity of serum catalase based on butyl rhodamine B fluorescence quenching method | 甘肃医学院 | 2022-04-26 | — | — | CN | disclosed |