Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.77 |
| ▸ | TDO2 | P48775 | 7/20 | 0.77 |
| ▸ | EED | O75530 | 5/20 | 0.63 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.63 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CES2 | O00748 | 1/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | TERT | O14746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone Iia SCHEMBL2026738 | 0.78 | EED (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL30923422 | 0.76 | IDO1 (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL14417695 | 0.75 | EED (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL14417701 | 0.75 | EED (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL16152287 | 0.75 | EED (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL16152326 | 0.73 | EED (0.78) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL16152261 | 0.72 | IDO1 (1.00) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL16023776 | 0.72 | EED (0.65) | IDO1TDO2EEDSUZ12EZH2 | |
| SCHEMBL30978884 | 0.71 | IDO1 (0.61) | IDO1TDO2EEDSUZ12EZH2 | |
| Tanshinone Iib SCHEMBL14417728 | 0.71 | EED (1.00) | IDO1TDO2EEDSUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118021812-A | Nidaminib targeting compositions | 北京睿创康泰医药研究院有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118252882-A | Traditional Chinese medicine for treating scar | 保定市第五医院(保定市莲池区中心医院) | 2024-06-28 | — | — | CN | disclosed |
| CN-118206613-A | Refining method of tanshinone IIA analogue | 上海上药第一生化药业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118021812-A | Nidaminib targeting compositions | 北京睿创康泰医药研究院有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112098563-B | Detection method for chemical components of kidney-tonifying and blood-activating formula | 中国中医科学院望京医院(中国中医科学院骨伤科研究所) | 2022-07-15 | — | — | CN | disclosed |
| CN-114392298-A | Double-fermentation extraction process and preparation method of salvia miltiorrhiza root and cotton rose hibiscus leaf | 云南柏脉生物科技有限公司昆明分公司 | 2022-04-26 | — | — | CN | disclosed |