Tanshinone Iia

Tanshinone Iia

SCHEMBL2026738

Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCCC2(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EED O75530 5/20 1.00
▸ SUZ12 Q15022 5/20 1.00
▸ EZH2 Q15910 5/20 1.00
▸ MEN1 O00255 5/20 1.00
▸ ALDH1A1 P00352 5/20 1.00
▸ KMT2A Q03164 5/20 1.00
▸ CES2 O00748 4/20 1.00
▸ HPGD P15428 4/20 1.00
▸ HSD17B10 Q99714 4/20 1.00
▸ HIF1A Q16665 3/20 1.00
▸ EPAS1 Q99814 3/20 1.00
▸ KDM4E B2RXH2 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ RECQL P46063 3/20 1.00
▸ TDP1 Q9NUW8 3/20 1.00
▸ POLB P06746 2/20 1.00
▸ CES1 P23141 2/20 1.00
▸ PTPN6 P29350 2/20 1.00
▸ PTPN11 Q06124 2/20 1.00
▸ NSD1 Q96L73 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16023777 0.91 EED (0.84) EEDSUZ12EZH2MEN1ALDH1A1
SCHEMBL29538928 0.91 EED (0.84) EEDSUZ12EZH2MEN1ALDH1A1
SCHEMBL16152326 0.88 EED (0.78) EEDSUZ12EZH2MEN1ALDH1A1
Przewaquinone A SCHEMBL16152272 0.85 IDO1 (1.00) EEDSUZ12EZH2MEN1ALDH1A1
Tanshinone Iib SCHEMBL14417728 0.84 EED (1.00) EEDSUZ12EZH2MEN1ALDH1A1
Tanshinone Iib SCHEMBL11945767 0.84 EED (1.00) EEDSUZ12EZH2MEN1ALDH1A1
Methyl Tanshinonate SCHEMBL14417730 0.83 EED (1.00) EEDSUZ12EZH2MEN1ALDH1A1
SCHEMBL17663613 0.83 EED (0.77) EEDSUZ12EZH2MEN1ALDH1A1
Methyl Tanshinonate SCHEMBL16152293 0.83 EED (1.00) EEDSUZ12EZH2MEN1ALDH1A1
SCHEMBL14417696 0.82 EED (0.76) EEDSUZ12EZH2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075435-A Brain-targeted neutral granulocyte membrane-encapsulated tanshinone IIa PLGA nano preparation and preparation method and application thereof — 2026-05-26 — — CN claimed
CN-122067093-A Multi-source remote sensing image-based dual-target prediction method for yield-quality of red sage root 河南大学 2026-05-19 — — CN claimed
CN-122059742-A Compound foliar fertilizer, preparation method and application thereof 易博生物科技(青岛)有限公司 2026-05-19 — — CN claimed
CN-122005659-A Pharmaceutical composition for treating burns and scalds in intensive care and preparation method thereof 养系列(山东)生物科技有限公司 2026-05-12 — — CN claimed
CN-122005655-A Magnetic nano-drug carrier 中国中医科学院广安门医院 2026-05-12 — — CN claimed
CN-122011116-A Salvia SmCLE-3 polypeptide and preparation method and application thereof 易博生物科技(青岛)有限公司 2026-05-12 — — CN claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 — — EP claimed
US-20260061062-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM UNIV NEBRASKA (US) 2026-03-05 — — US claimed
CN-121583384-A Nucleic acid-small molecule non-covalent complex and preparation method and application thereof 上海中医药大学 2026-02-27 — — CN claimed
US-12496349-B2 Macromolecular prodrug-based thermosensitive injectable gel as a novel drug delivery platform BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2025-12-16 — — US claimed
CN-112345679-B Fingerprint characteristic spectrum of Wuling preparation, establishing method and application thereof 清华德人西安幸福制药有限公司 2022-03-01 — — CN claimed
CN-111667889-B Method for predicting content of quality marker in salvia miltiorrhiza 山东中医药大学 2022-03-01 — — CN claimed
CN-114081990-A Traditional Chinese medicine composite temperature-sensitive gel embolic agent as well as preparation method and application thereof 江苏省中医药研究院 2022-02-25 — — CN claimed
CN-114085264-A A method for preparing tanshinone IIA extracted from Saviae Miltiorrhizae radix 河南省康华药业股份有限公司 2022-02-25 — — CN claimed
CN-110907576-B Method for simultaneously determining content of 16 active ingredients in Guanxinjing capsule 河北医科大学 2022-02-11 — — CN claimed
CN-113975264-A Method for preventing or treating side effects of tumor therapy 上海岸阔医药科技有限公司 2022-01-28 — — CN claimed
CN-113980087-A Method for preparing tanshinone IIA sodium sulfonate 上海上药第一生化药业有限公司 2022-01-28 — — CN claimed
CN-113967267-A Endoplasmic reticulum targeting of fatty acid modified albumin and uses thereof 四川大学 2022-01-25 — — CN claimed
WO-2016160880-A1 METHODS AND COMPOSITIONS FOR TREATING PANCREATITIS BAYLOR RESEARCH INSTITUTE (US) 2016-10-06 — — WO claimed
WO-2015194710-A1 COMPOSITION COMPRISING MESENCHYMAL STEM CELLS TREATED WITH STAT3 INHIBITOR AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING IMMUNE DISEASES 가톨릭대학교 산학협력단 2015-12-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061062-A1 MACROMOLECULAR PRODRUG-BASED THERMOSENSITIVE INJECTABLE GEL AS A NOVEL DRUG DELIVERY PLATFORM CD44, ALG1, HSF1 EED 4656/4885SUZ12 4677/4885EZH2 3726/4885
US-12496349-B2 Macromolecular prodrug-based thermosensitive injectable gel as a novel drug delivery platform PLG, PYGL, PPIG EED 4846/4885SUZ12 4840/4885EZH2 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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