Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372310 | 1.00 | LMNA (0.47) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| Acetic Acid SCHEMBL27621956 | 0.95 | TSHR (0.44) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| SCHEMBL29096390 | 0.85 | SMN1; SMN2 (0.35) | LMNASMN1; SMN2TSHRKDM4ECYP2C19 | |
| SCHEMBL21678003 | 0.83 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| SCHEMBL27317635 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| SCHEMBL16352990 | 0.81 | CHRM2 (0.47) | LMNASMN1; SMN2TSHRCYP1A2MAPT | |
| SCHEMBL7860482 | 0.81 | P2RX4 (0.40) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| SCHEMBL30105986 | 0.81 | P2RX4 (0.40) | LMNASMN1; SMN2TSHRKDM4ECYP1A2 | |
| SCHEMBL27581285 | 0.81 | FABP7 (0.47) | LMNATSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8378960 | 0.80 | POLB (0.37) | LMNASMN1; SMN2KDM4EALDH1A1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874209-A | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110461838-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-05-06 | — | — | CN | disclosed |