SCHEMBL295401

SCHEMBL295401

C/C(=C\c1ccccc1)CO

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
AKR1C3 P42330 1/20 0.50
TRPA1 O75762 1/20 0.48
ALOX15 P16050 2/20 0.47
USP2 O75604 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
RECQL P46063 1/20 0.47
FBP1 P09467 1/20 0.45
GRIK1 P39086 1/20 0.45
GRIK2 Q13002 1/20 0.45
KDM1A O60341 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MTNR1A P48039 2/20 0.42
MTNR1B P49286 2/20 0.42
HTT P42858 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078610 1.00 TSHR (0.50) TSHRALDH1A1AKR1C3TRPA1ALOX15
SCHEMBL295402 1.00 TSHR (0.50) TSHRALDH1A1AKR1C3TRPA1ALOX15
SCHEMBL28581850 0.84 CYP3A4 (0.45) TSHRALDH1A1AKR1C3TRPA1ALOX15
SCHEMBL11592843 0.82 FBP1 (0.47) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL11592847 0.82 FBP1 (0.47) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL5027068 0.81 TSHR (0.50) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL110774 0.81 TSHR (0.50) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL598599 0.81 TSHR (0.50) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL2211881 0.79 TSHR (0.48) TSHRALDH1A1AKR1C3ALOX15USP2
SCHEMBL1758165 0.79 CYP2A6 (0.41) SMN1; SMN2RECQLKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302728-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD SYMRISE AG (DE) 2025-10-02 US claimed
EP-4526411-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD Symrise AG (DE) 2025-03-26 EP claimed
CN-119403907-A Fragrance composition and product for delivering positive emotion 西姆莱斯有限公司 2025-02-07 CN claimed
CN-117142916-A Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2023-12-01 CN claimed
WO-2023224604-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD SYMRISE AG (DE) 2023-11-23 WO claimed
WO-2023222753-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD SYMRISE AG (DE) 2023-11-23 WO claimed
CN-115716776-A Method for synthesizing alcohol compound by catalyzing alpha, beta-unsaturated aldehyde 化学与精细化工广东省实验室 2023-02-28 CN claimed
CN-113277963-B Amine compound and preparation method and application thereof 南京工业大学 2022-11-04 CN claimed
CN-113277963-A Amine compound and preparation method and application thereof 南京工业大学 2021-08-20 CN claimed
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
US-6740699-B2 EMULSION POLYMERIZATION OF CYCLOHEXENE-STABILIZED SOLUTION OF METHALLYL ALCOHOL; PHOTOSTABILITY ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2004-05-25 US claimed
EP-1363952-A1 METHOD FOR OBTAINING A STABILISED PHOTOCHROMIC LATEX, LATEX OBTAINED AND USE IN OPHTHALMIC OPTICS ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-11-26 EP claimed
US-20030100672-A1 Method for obtaining a stabilized photochromic latex, latex obtained, and application to ophthalmic optics ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2003-05-29 US claimed
EP-1056739-B1 NOVEL CYCLIC PRO-PERFUMES HAVING MODIFIABLE FRAGRANCE RAW MATERIAL ALCOHOL RELEASE RATE PROCTER & GAMBLE (US) 2003-05-02 EP claimed
US-6500797-B1 Process for preparing β-ketoester fragrance pro-accords from 1,3-dioxan-4,6-diones THE PROCTER & GAMBLE COMPANY 2002-12-31 US claimed
WO-2002055564-A1 METHOD FOR OBTAINING A STABILISED PHOTOCHROMIC LATEX, LATEX OBTAINED AND USE IN OPHTHALMIC OPTICS ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-07-18 WO claimed
US-5741831-A Polymerizable compositions based on thio (meth) acrylate monomers, polymers with a low yellow index obtained from such compositions, and corresponding ophthalmic lenses ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-04-21 US claimed
US-5702825-A PHOTOPOLYMERIZATION; PHOSPHINIC ANTICOLORING AGENT ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 1997-12-30 US claimed
EP-0745620-B1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INT (FR) 1997-10-29 EP claimed
EP-0745620-A1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed