Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16288088 | 1.00 | PTPN1 (0.48) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL27222134 | 1.00 | PTPN1 (0.48) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL1739174 | 0.92 | MDM4 (0.54) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL10020438 | 0.92 | MDM4 (0.54) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL4404683 | 0.91 | PTPN1 (0.49) | PTPN1MDM4TP53SLC17A5 | |
| SCHEMBL14788934 | 0.88 | MDM4 (0.51) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL16288510 | 0.86 | MDM4 (0.45) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL31683953 | 0.86 | MDM4 (0.45) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL16288514 | 0.86 | MDM4 (0.45) | PTPN1MDM4TP53SLC17A5CASP3 | |
| SCHEMBL17431965 | 0.86 | MDM4 (0.55) | PTPN1MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12415835-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-09-16 | — | — | US | disclosed |
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891457-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | PTPN1 4035/4885MDM4 3559/4885TP53 2654/4885 |
| US-12415835-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | PTPN1 4035/4885MDM4 3559/4885TP53 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.