SCHEMBL1739174

SCHEMBL1739174

CC(C)(C)SSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ SLC17A5 Q9NRA2 1/20 0.53
▸ CASP3 P42574 3/20 0.53
▸ TLR2 O60603 2/20 0.48
▸ MDM2 Q00987 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020438 1.00 MDM4 (0.54) MDM4TP53SLC17A5CASP3TLR2
SCHEMBL31197005 0.94 MDM4 (0.54) MDM4TP53SLC17A5CASP3TLR2
SCHEMBL13253077 0.92 CASP3 (0.48) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL29540266 0.92 PTPN1 (0.48) MDM4TP53SLC17A5CASP3
SCHEMBL16288088 0.92 PTPN1 (0.48) MDM4TP53SLC17A5CASP3
SCHEMBL27222134 0.92 PTPN1 (0.48) MDM4TP53SLC17A5CASP3
SCHEMBL6517147 0.90 CASP3 (0.47) MDM4TP53SLC17A5CASP3
SCHEMBL27008576 0.90 MDM4 (0.49) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL27129147 0.90 MDM4 (0.49) MDM4TP53SLC17A5CASP3MDM2
SCHEMBL7592482 0.90 MDM4 (0.46) MDM4TP53SLC17A5CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118490852-A Intracellular-constructed legumain-responded PET/MR bimodal molecular probe and application thereof 安徽医科大学第一附属医院 2024-08-16 — — CN claimed
CN-114957388-B Short peptide fluorescent probe and preparation method and application thereof 国家纳米科学中心 2024-04-30 — — CN claimed
CN-115010786-B GSH-hypoxia microenvironment double-response self-assembled fluorescent probe and preparation method and application thereof 国家纳米科学中心 2024-03-12 — — CN claimed
CN-115010786-A GSH-hypoxic microenvironment dual-response self-assembly fluorescent probe and preparation method and application thereof 国家纳米科学中心 2022-09-06 — — CN claimed
CN-114957388-A Short peptide fluorescent probe and preparation method and application thereof 国家纳米科学中心 2022-08-30 — — CN claimed
CN-114616236-A Process for preparing cysteic acid-containing polypeptides 江苏金斯瑞生物科技有限公司 2022-06-10 — — CN claimed
CN-113956333-B Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-03-29 — — CN claimed
CN-114867527-B Macrocyclic peptides Herantis pharmaceutical Co. (FI) 2026-05-26 — — CN disclosed
CN-122011071-A Synthesis method and application of DNA-ketoamide conjugate 重庆大学 2026-05-12 — — CN disclosed
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-20 — — US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
EP-4611793-A1 INSULIN DERIVATIVES Ustav organicke chemie a biochemie Akademie ved CR, v.v.i. (CZ) 2025-09-10 — — EP disclosed
US-20250243290-A1 AGONISTIC ANTI-TUMOR NECROSIS FACTOR RECEPTOR 2 ANTIBODIES THE GENERAL HOSPITAL CORPORATION 2025-07-31 — — US disclosed
EP-0833648-A4 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES JOLLA PHARMA (US) 1999-10-13 — — EP disclosed
EP-0954531-A4 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LAJOLLA PHARMACEUTICAL COMPANY (US) 1999-08-31 — — EP disclosed
WO-1997046251-A9 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES — 1998-06-04 — — WO disclosed
EP-0833648-A1 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LA JOLLA PHARMACEUTICAL (US) 1998-04-08 — — EP disclosed
WO-1997046251-A1 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LAJOLLA PHARMACEUTICAL COMPANY (US) 1997-12-11 — — WO disclosed
WO-1996040197-A9 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES — 1997-04-24 — — WO disclosed
WO-1996040197-A1 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LA JOLLA PHARMACEUTICAL COMPANY (US) 1996-12-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION VIP, NPPA, DNPEP MDM4 3469/4885TP53 3832/4885SLC17A5 3772/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R MDM4 3559/4885TP53 2654/4885SLC17A5 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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