SCHEMBL29540403

SCHEMBL29540403

FC1(F)c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.48
AKR1A1 P14550 1/20 0.42
AKR1B1 P15121 1/20 0.42
S100A4 P26447 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
TDP2 O95551 1/20 0.38
PTPRC P08575 1/20 0.35
METAP1 P53582 1/20 0.35
BCL2 P10415 2/20 0.34
MCL1 Q07820 1/20 0.34
CYP2A6 P11509 2/20 0.33
TGM2 P21980 1/20 0.33
CES1 P23141 1/20 0.33
KDM1A O60341 1/20 0.33
AHR P35869 2/20 0.32
CMA1 P23946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206283 1.00 PDK2 (0.48) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL13231061 0.95 PDK2 (0.46) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL17880891 0.89 PDK2 (0.59) PDK2AKR1A1AKR1B1S100A4PTPRC
SCHEMBL19764175 0.89 PDK2 (0.48) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL8750737 0.88 PDK2 (0.41) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL20407051 0.88 PDK2 (0.41) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL2707552 0.88 PDK2 (0.41) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL7605853 0.85 PDK2 (0.48) PDK2AKR1A1AKR1B1S100A4CA1
SCHEMBL30882393 0.83 PDK2 (0.45) PDK2AKR1A1AKR1B1KDM1A
SCHEMBL29294764 0.83 ALDH1A1 (0.44) PDK2AKR1A1AKR1B1S100A4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4045568-B1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES SOLVAY SPECIALTY POLYMERS USA (US) 2025-05-21 EP claimed
CN-118852590-A Poly (2, 7-di (nitrogen carbazolyl) -9, 9-difluoro fluorene) and synthetic method and application thereof 中国石油天然气集团有限公司 2024-10-29 CN claimed
CN-114402013-B Poly (arylene sulfide) polymer and corresponding polymer composition and article 索尔维特殊聚合物美国有限责任公司 2024-04-19 CN claimed
CN-115107161-A Concrete slab production system and concrete slab 俞滢滢 2022-09-27 CN claimed
EP-4045568-A1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES Solvay Specialty Polymers USA, LLC. (US) 2022-08-24 EP claimed
CN-114402013-A Poly (aryl sulfide) polymers and corresponding polymer compositions and articles 索尔维特殊聚合物美国有限责任公司 2022-04-26 CN claimed
CN-114929676-B Heterocyclic carboxylate compounds as glycolate oxidase inhibitors 紫丁香疗法有限公司 2025-04-29 CN disclosed
CN-118852590-A Poly (2, 7-di (nitrogen carbazolyl) -9, 9-difluoro fluorene) and synthetic method and application thereof 中国石油天然气集团有限公司 2024-10-29 CN disclosed
CN-118852590-A Poly (2, 7-di (nitrogen carbazolyl) -9, 9-difluoro fluorene) and synthetic method and application thereof 中国石油天然气集团有限公司 2024-10-29 CN disclosed
CN-114402013-B Poly (arylene sulfide) polymer and corresponding polymer composition and article 索尔维特殊聚合物美国有限责任公司 2024-04-19 CN disclosed
CN-115107161-A Concrete slab production system and concrete slab 俞滢滢 2022-09-27 CN disclosed
CN-115107161-A Concrete slab production system and concrete slab 俞滢滢 2022-09-27 CN disclosed
EP-4045568-A1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES Solvay Specialty Polymers USA, LLC. (US) 2022-08-24 EP disclosed
CN-114929676-A Heterocyclic carboxylate compounds as glycolate oxidase inhibitors 紫丁香疗法有限公司 2022-08-19 CN disclosed
CN-114402013-A Poly (aryl sulfide) polymers and corresponding polymer compositions and articles 索尔维特殊聚合物美国有限责任公司 2022-04-26 CN disclosed