Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15123451 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL15123452 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL964581 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL30628704 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL26105356 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL26105361 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL23894144 | 0.77 | PSMB5 (0.53) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL24764542 | 0.77 | MME (0.42) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL10076082 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT | |
| SCHEMBL4811341 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2FAAHSLC6A5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12415835-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-09-16 | — | — | US | disclosed |
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| EP-3974563-A1 | CYCLIC PEPTIDES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2022-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891457-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | SMN1; SMN2 4620/4885FAAH 3575/4885SLC6A5 3991/4885 |
| US-12415835-B2 | Peptide-compound cyclization method | VIP, NGLY1, GLP1R | SMN1; SMN2 4620/4885FAAH 3575/4885SLC6A5 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.