Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22617352 | 0.92 | OGA (0.42) | OGAACHEALDH1A1PIK3CACYP2C9 | |
| SCHEMBL23834566 | 0.88 | OGA (0.50) | OGAACHEALDH1A1PIK3CACYP2C9 | |
| SCHEMBL17437956 | 0.82 | OGA (0.53) | OGAACHEALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL30612636 | 0.81 | OGA (0.54) | OGAACHEALDH1A1PIK3CAPSMB8 | |
| SCHEMBL12803550 | 0.81 | OGA (0.48) | OGAACHEALDH1A1PIK3CACYP2C9 | |
| SCHEMBL31352440 | 0.79 | ACHE (0.59) | OGAACHEALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22979376 | 0.79 | ACHE (0.56) | OGAACHEALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22617414 | 0.78 | OGA (0.46) | OGAACHEALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22617315 | 0.78 | OGA (0.46) | OGAACHEALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL22617317 | 0.78 | OGA (0.46) | OGAACHEALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401952-A | Substituted cycloalkyl compounds as modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-04-26 | — | — | CN | disclosed |