SCHEMBL29541978

SCHEMBL29541978

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc4cc(-c5ccc6ccccc6c5)ccc4c3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.52
ESR2 Q92731 3/20 0.52
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
ACMSD Q8TDX5 1/20 0.46
CYP17A1 P05093 1/20 0.46
CYP19A1 P11511 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
ALOX5 P09917 2/20 0.46
BACE1 P56817 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CYP1A1 P04798 1/20 0.43
CYP1B1 Q16678 1/20 0.43
GSTP1 P09211 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20296876 1.00 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL24686644 1.00 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL19998766 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL20313391 0.98 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL24029043 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL14263647 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL14263582 0.98 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL20313408 0.96 ESR1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL21718308 0.96 HSD17B1 (0.50) ESR1ESR2HSD17B1HSD17B2ACMSD
SCHEMBL23095516 0.96 ESR1 (0.52) ESR1ESR2HSD17B1HSD17B2ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716328-A Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2022-07-08 CN disclosed
CN-108258131-B Organic compound, light-emitting element, light-emitting device, electronic device, display device, and lighting device 株式会社半导体能源研究所 2022-05-24 CN disclosed