Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29692756 | 0.99 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL740253 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL11440079 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL30182028 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL29543824 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL29543689 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| Bromide SCHEMBL29543703 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| Bromide SCHEMBL30261894 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL11426363 | 0.80 | CA12 (0.59) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL30526125 | 0.79 | CA12 (0.58) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492422-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | Sunbird Bio, Inc. (US) | 2025-12-09 | — | — | US | disclosed |
| WO-2024040009-A2 | INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 AND METHODS OF PREPARATION AND USES THEREOF | PRIMETIME LIFE SCIENCES, LLC (US) | 2024-02-22 | — | — | WO | disclosed |
| US-11851697-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | GLYMPSE BIO, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20220128567-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-04-28 | — | — | US | disclosed |
| US-20220128546-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-04-28 | — | — | US | disclosed |