Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.79 |
| ▸ | TACR1 | P25103 | 1/20 | 0.79 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.79 |
| ▸ | HTR2B | P41595 | 1/20 | 0.79 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709845 | 1.00 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18890304 | 1.00 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18890327 | 0.92 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18890331 | 0.92 | GLS (1.00) | GLS | |
| SCHEMBL29543847 | 0.92 | GLS (1.00) | GLS | |
| SCHEMBL18890322 | 0.92 | GLS (1.00) | GLS | |
| SCHEMBL18890303 | 0.92 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL18890293 | 0.92 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29393866 | 0.92 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29544416 | 0.92 | GLS (1.00) | GLSSLC6A2TACR1OPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349967-B | 1,3, 4-thiadiazole compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2022-02-15 | — | — | CN | disclosed |