Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949616 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL19831023 | 0.90 | CYP11B1 (0.47) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL30835111 | 0.90 | CYP11B1 (0.47) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL14142014 | 0.83 | PIK3CD (0.47) | KDM4EALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL30835081 | 0.79 | CYP3A4 (0.44) | KDM4EALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL14141645 | 0.77 | PIM1 (0.42) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL4455356 | 0.77 | CKS1B (0.42) | ALDH1A1L3MBTL1NPC1POLBMAPT | |
| SCHEMBL3822384 | 0.75 | HIF1A (0.64) | KDM4EALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL19819285 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1NPC1LMNA | |
| SCHEMBL30835003 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4586911-A1 | LUMINESCENT ENZYME-BASED SENSORS | Terumo Cardiovascular Systems Corporation (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2024059143-A1 | LUMINESCENT ENZYME-BASED SENSORS | TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-116656795-A | Nucleotide derivatives and methods of use thereof | 纽约哥伦比亚大学董事会 | 2023-08-29 | — | — | CN | disclosed |
| EP-4110952-A2 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2022251242-A1 | COMPOSITIONS AND METHODS FOR MODIFYING DNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-01 | — | — | WO | disclosed |
| EP-4081653-A1 | METHODS FOR LONG READ SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-114989235-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-09-02 | — | — | CN | disclosed |
| CN-114981283-A | Novel nucleotide analogs and methods of use | 纽约市哥伦比亚大学信托人 | 2022-08-30 | — | — | CN | disclosed |
| CN-108779138-B | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-06-17 | — | — | CN | disclosed |
| EP-3997101-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-18 | — | — | EP | disclosed |