Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29536174 | 0.91 | CA12 (0.66) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL29543774 | 0.89 | CA12 (0.69) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL3275292 | 0.89 | CA12 (0.69) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL22882751 | 0.89 | CA12 (0.69) | CA12CA1CA9TDP1RAB9A | |
| Hydrochloric Acid SCHEMBL29402049 | 0.88 | CA12 (0.67) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL29543989 | 0.87 | KDM4E (0.61) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL14176759 | 0.86 | CA12 (0.72) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL5706432 | 0.83 | CA12 (0.62) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL29543713 | 0.83 | CA12 (0.62) | CA12CA1CA9TDP1RAB9A | |
| SCHEMBL571383 | 0.83 | CA12 (0.62) | CA12CA1CA9TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492422-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | Sunbird Bio, Inc. (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250297300-A1 | DETECTION, STAGING, MONITORING AND TREATING A DISEASE OR A CONDITION | Sunbird Bio, Inc. | 2025-09-25 | — | — | US | disclosed |
| US-20250223627-A1 | FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE DETECTION IN BIOFLUIDS | Sunbird Bio, Inc. | 2025-07-10 | — | — | US | disclosed |
| US-20250215476-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR HEPATOCELLULAR CARCINOMA | Sunbird Bio, Inc. | 2025-07-03 | — | — | US | disclosed |
| US-20250197917-A1 | METHOD OF PROTEASE DETECTION | Sunbird Bio, Inc. | 2025-06-19 | — | — | US | disclosed |
| US-12305217-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | Sunbird Bio, Inc. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20250110130-A1 | EX VIVO PROTEASE ACTIVATION AND DETECTION | Sunbird Bio, Inc. | 2025-04-03 | — | — | US | disclosed |
| US-20250092437-A1 | DISEASE DETECTION WITH COMBINATORIAL BIOMARKERS | Sunbird Bio, Inc. | 2025-03-20 | — | — | US | disclosed |
| US-11851697-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | GLYMPSE BIO, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20230175037-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-11604193-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | GLYMPSE BIO, INC. (US) | 2023-03-14 | — | — | US | disclosed |
| US-20220178935-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-06-09 | — | — | US | disclosed |
| US-20220128546-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-04-28 | — | — | US | disclosed |
| US-20220128567-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-04-28 | — | — | US | disclosed |