SCHEMBL3275292

SCHEMBL3275292

Cc1cc(=O)oc2cc(NC(=O)[C@H](C)N)ccc12

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 3/20 0.69
▸ CA1 P00915 3/20 0.69
▸ CA9 Q16790 3/20 0.69
▸ TDP1 Q9NUW8 2/20 0.66
▸ RAB9A P51151 6/20 0.62
▸ KDM4E B2RXH2 5/20 0.62
▸ ALDH1A1 P00352 5/20 0.62
▸ NPC1 O15118 5/20 0.62
▸ HPGD P15428 4/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.62
▸ HSD17B10 Q99714 2/20 0.62
▸ GAA P10253 2/20 0.60
▸ GLA P06280 1/20 0.60
▸ MAPT P10636 1/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ CTDSP1 Q9GZU7 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22882751 1.00 CA12 (0.69) CA12CA1CA9TDP1RAB9A
SCHEMBL29543774 1.00 CA12 (0.69) CA12CA1CA9TDP1RAB9A
Hydrochloric Acid SCHEMBL29402049 0.99 CA12 (0.67) CA12CA1CA9TDP1RAB9A
Trifluoroacetic Acid SCHEMBL592896 0.92 TDP1 (0.61) CA12CA1CA9TDP1RAB9A
SCHEMBL29536174 0.90 CA12 (0.66) CA12CA1CA9TDP1RAB9A
SCHEMBL14176759 0.89 CA12 (0.72) CA12CA1CA9TDP1RAB9A
SCHEMBL29544277 0.89 CA12 (0.64) CA12CA1CA9TDP1RAB9A
SCHEMBL5706432 0.87 CA12 (0.62) CA12CA1CA9TDP1RAB9A
SCHEMBL29543713 0.87 CA12 (0.62) CA12CA1CA9TDP1RAB9A
SCHEMBL571384 0.87 CA12 (0.62) CA12CA1CA9TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064756-A MICROBIAL SUSCEPTIBILITY ASSAY USING 7-N-(AMINOACYL)-7-AMIDO-4-METHYLCOUMARINS SIEMENS HEALTHCARE DIAGNOSTICS INC. 1991-11-12 — — US claimed
WO-1983003624-A1 MICROBIOLOGICAL TEST PROCESSES AND APPARATUS UNILEVER PLC (GB) 1983-10-27 — — WO claimed
EP-4196181-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES 3M Innovative Properties Company (US) 2023-06-21 — — EP disclosed
US-11667945-B2 Detection method and detection probe for colibactin and colibactin-producing bacteria SHIZUOKA PREFECTURE PUBLIC UNIVERSITY CORPORATION (JP) 2023-06-06 — — US disclosed
WO-2022263950-A1 BIOLOGICAL INDICATOR WITH ADJUSTED RESISTANCE CHARACTERISTICS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-22 — — WO disclosed
WO-2022034498-A1 MOVING-FRONT STERILIZATION MONITORING DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-02-17 — — WO disclosed
US-20210010051-A1 DETECTION METHOD AND DETECTION PROBE FOR COLIBACTIN AND COLIBACTIN-PRODUCING BACTERIA SHIZUOKA PREFECTURE PUBLIC UNIVERSITY CORPORATION (JP) 2021-01-14 — — US disclosed
EP-2877591-B1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX SA (FR) 2018-01-10 — — EP disclosed
US-9562899-B2 Method of detecting OXA-048 carbapenemase producing bacteria bioMérieux (FR) 2017-02-07 — — US disclosed
US-20150160211-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA BIOMERIEUX (FR) 2015-06-11 — — US disclosed
EP-2877591-A1 METHOD OF DETECTING OXA-048 CARBAPENEMASE PRODUCING BACTERIA Biomérieux (FR) 2015-06-03 — — EP disclosed
EP-0516814-A1 METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS. BAXTER DIAGNOSTICS INC (US) 1992-12-09 — — EP disclosed
WO-1992012257-A1 METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS BAXTER DIAGNOSTICS INC. (US) 1992-07-23 — — WO disclosed
US-5079144-A Test For Antibiotic Sensitivity Or For Minimum Inhibitory Concentration Of The Antibiotic RADIOMETER CORPORATE DEVELOPMENT LTD. (GB) 1992-01-07 — — US disclosed
US-5064756-A MICROBIAL SUSCEPTIBILITY ASSAY USING 7-N-(AMINOACYL)-7-AMIDO-4-METHYLCOUMARINS SIEMENS HEALTHCARE DIAGNOSTICS INC. 1991-11-12 — — US disclosed
US-5064756-A MICROBIAL SUSCEPTIBILITY ASSAY USING 7-N-(AMINOACYL)-7-AMIDO-4-METHYLCOUMARINS SIEMENS HEALTHCARE DIAGNOSTICS INC. 1991-11-12 — — US disclosed
EP-0335354-A2 Rapid and sensitive low pressure enzyme detection and measurement system BioControl Systems, Incorporated (US) 1989-10-04 — — EP disclosed
EP-0091837-B1 MICROBIOLOGICAL TEST PROCESSES AND APPARATUS RADIOMETER CORPORATE DEVELOPMENT LIMITED (GB) 1989-07-26 — — EP disclosed
WO-1983003624-A1 MICROBIOLOGICAL TEST PROCESSES AND APPARATUS UNILEVER PLC (GB) 1983-10-27 — — WO disclosed
EP-0091837-A1 Microbiological test processes and apparatus RADIOMETER CORPORATE DEVELOPMENT LIMITED (GB) 1983-10-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210010051-A1 DETECTION METHOD AND DETECTION PROBE FOR COLIBACTIN AND COLIBACTIN-PRODUCING BACTERIA CLTB, LNPEP, CMBL CA12 1318/4885CA1 2181/4885CA9 2947/4885
US-11667945-B2 Detection method and detection probe for colibactin and colibactin-producing bacteria CLTB, LNPEP, CMBL CA12 1318/4885CA1 2181/4885CA9 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback