Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950 | 0.98 | NR1H2 (0.43) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| Selenium SCHEMBL30289776 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL22498864 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL28994299 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| Bromide SCHEMBL8589844 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| Water SCHEMBL7382263 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL10635278 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL29402664 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL3962514 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E | |
| SCHEMBL27926367 | 0.95 | NR1H2 (0.42) | NR1H2NR1H3BTKALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | claimed |
| US-7759488-B2 | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| CN-101495459-A | Monoazole ligand platinum analogs | BIONUMERIK PHARMACEUTICALS INC (US) | 2009-07-29 | — | — | CN | disclosed |
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | BIONUMERIK PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004696-A1 | cis-aminedichloro [1-(phenylsulfonyl)-1H-benzotriazole] platinum for complexing with DNA and/or RNA | POLRMT, LUC7L2, NSUN3 | NR1H2 2902/4885NR1H3 2546/4885BTK 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.