Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687457 | 1.00 | OPRK1 (0.54) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL29410184 | 1.00 | OPRK1 (0.54) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL6125005 | 0.90 | OPRK1 (0.51) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL11964613 | 0.89 | OPRK1 (0.62) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL13421271 | 0.89 | OPRK1 (0.48) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL2266031 | 0.89 | OPRK1 (0.55) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL13421407 | 0.87 | OPRK1 (0.59) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL605960 | 0.87 | OPRK1 (0.51) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL8985784 | 0.87 | OPRK1 (0.51) | OPRK1LMNAPDE3APDE4DHTR2B | |
| SCHEMBL2264662 | 0.87 | OPRK1 (0.53) | OPRK1LMNAPDE3APDE4DHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452989-A1 | MITOCHONDRIAL ATP INHIBITORS TARGETING THE GAMMA SUBUNIT PREVENT METASTASIS | Lunella Biotech, Inc. (CA) | 2024-10-30 | — | — | EP | disclosed |
| CN-118660899-A | Mitochondrial ATP inhibitors targeting gamma subunits prevent metastasis | 卢内拉生物技术有限公司 | 2024-09-17 | — | — | CN | disclosed |
| EP-4232432-A1 | MITOCHONDRIAL ATP INHIBITORS TARGETING THE GAMMA SUBUNIT PREVENT METASTASIS | Lunella Biotech, Inc. (CA) | 2023-08-30 | — | — | EP | disclosed |
| CN-116437922-A | Gamma subunit targeted mitochondrial ATP inhibitors for preventing metastasis | 卢内拉生物技术有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023119232-A1 | MITOCHONDRIAL ATP INHIBITORS TARGETING THE GAMMA SUBUNIT PREVENT METASTASIS | LUNELLA BIOTECH, INC. (CA) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022084947-A1 | MITOCHONDRIAL ATP INHIBITORS TARGETING THE GAMMA SUBUNIT PREVENT METASTASIS | LUNELLA BIOTECH, INC. (CA) | 2022-04-28 | — | — | WO | disclosed |