Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 5/20 | 0.38 |
| ▸ | TYK2 | P29597 | 9/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544530 | 0.88 | TYK2 (0.37) | TYK2EGFR | |
| SCHEMBL29544410 | 0.88 | TYK2 (0.38) | TYK2EGFR | |
| SCHEMBL29544730 | 0.86 | EGFR (0.42) | BUB1TYK2EGFR | |
| SCHEMBL29545774 | 0.85 | TYK2 (0.35) | BUB1TYK2EGFR | |
| SCHEMBL29544599 | 0.84 | EGFR (0.36) | TYK2RAF1EGFR | |
| SCHEMBL29544373 | 0.84 | TYK2 (0.41) | TYK2PARP1 | |
| SCHEMBL29544819 | 0.84 | EGFR (0.37) | TYK2EGFR | |
| SCHEMBL29544583 | 0.83 | TYK2 (0.40) | TYK2 | |
| SCHEMBL29545250 | 0.83 | TYK2 (0.40) | TYK2 | |
| SCHEMBL29545283 | 0.83 | TYK2 (0.38) | TYK2RAF1EGFRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |