Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.35 |
| ▸ | BUB1 | O43683 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544530 | 0.90 | TYK2 (0.37) | TYK2EGFRIDO1 | |
| SCHEMBL29544410 | 0.88 | TYK2 (0.38) | TYK2EGFRIDO1 | |
| SCHEMBL29544491 | 0.85 | BUB1 (0.38) | TYK2BUB1EGFR | |
| SCHEMBL29545250 | 0.83 | TYK2 (0.40) | TYK2 | |
| SCHEMBL29544583 | 0.83 | TYK2 (0.40) | TYK2 | |
| SCHEMBL29545263 | 0.83 | TYK2 (0.49) | TYK2 | |
| SCHEMBL29544808 | 0.83 | TYK2 (0.39) | TYK2 | |
| SCHEMBL29545624 | 0.83 | TYK2 (0.36) | TYK2EGFRIDO1 | |
| SCHEMBL29544949 | 0.83 | TYK2 (0.40) | TYK2 | |
| SCHEMBL29544662 | 0.83 | TYK2 (0.39) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |