Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31440156 | 0.83 | HSP90AA1 (0.39) | PIK3CAPIK3R1BUB1BCHEHSP90AA1 | |
| SCHEMBL15091349 | 0.82 | BUB1 (0.37) | PIK3CAPIK3R1BUB1BCHEHSP90AA1 | |
| SCHEMBL25394175 | 0.78 | ELANE (0.41) | PIK3CAPIK3R1SSTR4BCHEGPR119 | |
| SCHEMBL31050053 | 0.78 | ELANE (0.41) | PIK3CAPIK3R1SSTR4BCHEGPR119 | |
| SCHEMBL31355592 | 0.78 | ACLY (0.39) | PIK3CAPIK3R1BUB1BCHEHSP90AA1 | |
| SCHEMBL29522590 | 0.78 | PIK3CA (0.38) | PIK3CAPIK3R1BUB1SSTR4BCHE | |
| SCHEMBL138212 | 0.78 | PIK3CA (0.38) | PIK3CAPIK3R1BUB1SSTR4BCHE | |
| SCHEMBL19667735 | 0.78 | PIK3R1 (0.38) | PIK3CAPIK3R1BUB1BCHEHSP90AA1 | |
| SCHEMBL30935087 | 0.77 | ELANE (0.51) | PIK3CAPIK3R1BUB1BCHEHSP90AA1 | |
| SCHEMBL759396 | 0.74 | SLC22A12 (0.48) | PIK3CABUB1BCHEHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |