SCHEMBL29544698

SCHEMBL29544698

O=C1NCCn2nc(Br)c(Cl)c21

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.36
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31729148 0.79 CDC7 (0.36) CDC7
SCHEMBL30964225 0.79 CDC7 (0.36) CDC7PARP1
SCHEMBL29544632 0.79 CDC7 (0.36) CDC7
SCHEMBL29544725 0.78
SCHEMBL9941363 0.76 CDC7 (0.33) CDC7PARP1
SCHEMBL29544645 0.76 CDC7 (0.33) CDC7
SCHEMBL29544591 0.72 ALOX5 (0.31)
SCHEMBL29544593 0.72 CDC7 (0.52) CDC7PARP1
SCHEMBL24554284 0.70 RIPK3 (0.40) CDC7PARP1
SCHEMBL17129482 0.70 CDC7 (0.38) CDC7PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235872-A1 HETEROCYCLICS AS EGFR INHIBITORS SCHRÖDINGER, INC. (US) 2025-11-13 WO disclosed
WO-2022072634-A1 BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER SCORPION THERAPEUTICS, INC. (US) 2022-04-07 WO disclosed