Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | TYK2 | P29597 | 11/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544621 | 0.91 | TYK2 (0.34) | TYK2 | |
| SCHEMBL29544607 | 0.87 | EGFR (0.37) | EGFRTYK2ROCK2 | |
| SCHEMBL29544488 | 0.87 | EGFR (0.37) | EGFRTYK2ROCK2 | |
| SCHEMBL29545140 | 0.84 | EGFR (0.42) | EGFRTYK2ROCK2CYP3A4CYP2C8 | |
| SCHEMBL29544722 | 0.79 | TYK2 (0.40) | EGFRTYK2ROCK2 | |
| SCHEMBL29545127 | 0.78 | TYK2 (0.32) | TYK2 | |
| SCHEMBL29544930 | 0.78 | TYK2 (0.32) | TYK2 | |
| SCHEMBL29544658 | 0.78 | EGFR (0.38) | EGFRTYK2 | |
| SCHEMBL29544694 | 0.78 | EGFR (0.38) | EGFRTYK2 | |
| SCHEMBL29544839 | 0.77 | TYK2 (0.34) | EGFRTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |