Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 7/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.35 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.35 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.35 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545067 | 1.00 | CSF1R (0.38) | CSF1RSRCEGFRKDRDRD2 | |
| SCHEMBL29544467 | 1.00 | CSF1R (0.38) | CSF1RSRCEGFRKDRDRD2 | |
| SCHEMBL29544648 | 0.90 | RIPK2 (0.35) | SRCKDRGAKRIPK2COQ8A | |
| SCHEMBL29544685 | 0.90 | RIPK2 (0.35) | SRCKDRGAKRIPK2COQ8A | |
| SCHEMBL29544839 | 0.89 | TYK2 (0.34) | EGFRCCNT1CDK9TYK2 | |
| SCHEMBL29544621 | 0.85 | TYK2 (0.34) | CCNT1CDK9TYK2 | |
| SCHEMBL29544718 | 0.85 | TYK2 (0.32) | SRCCCNT1CDK9TYK2 | |
| SCHEMBL29545142 | 0.84 | CSF1R (0.39) | CSF1RSRCEGFRKDRPDGFRA | |
| SCHEMBL29545127 | 0.84 | TYK2 (0.32) | CCNT1CDK9TYK2 | |
| SCHEMBL29544930 | 0.84 | TYK2 (0.32) | CCNT1CDK9TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |