Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.35 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 6/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544685 | 1.00 | RIPK2 (0.35) | RIPK2GAKCOQ8ANLKKDR | |
| SCHEMBL29544467 | 0.90 | CSF1R (0.38) | RIPK2GAKCOQ8ANLKKDR | |
| SCHEMBL29544776 | 0.90 | CSF1R (0.38) | RIPK2GAKCOQ8ANLKKDR | |
| SCHEMBL29545067 | 0.90 | CSF1R (0.38) | RIPK2GAKCOQ8ANLKKDR | |
| SCHEMBL29544839 | 0.89 | TYK2 (0.34) | CCNT1CDK9TYK2 | |
| SCHEMBL29544718 | 0.84 | TYK2 (0.32) | CCNT1CDK9TYK2SRC | |
| SCHEMBL29544621 | 0.84 | TYK2 (0.34) | CCNT1CDK9TYK2 | |
| SCHEMBL29544930 | 0.83 | TYK2 (0.32) | CCNT1CDK9TYK2 | |
| SCHEMBL29545127 | 0.83 | TYK2 (0.32) | CCNT1CDK9TYK2 | |
| SCHEMBL29544629 | 0.82 | NCF1 (0.39) | CDK5CDK5R1KDM4CNCF1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |