Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544798 | 0.92 | EGFR (0.38) | EGFRABCG2ATMCSF1RPDGFRB | |
| SCHEMBL29545142 | 0.91 | CSF1R (0.39) | EGFRCSF1RPDGFRAKDRTYK2 | |
| SCHEMBL29545092 | 0.89 | EGFR (0.39) | EGFRCSF1RPDGFRAKDRMAPK1 | |
| SCHEMBL29544955 | 0.88 | EGFR (0.39) | EGFRCSF1RKDRTYK2CCNT1 | |
| SCHEMBL29544981 | 0.87 | EGFR (0.36) | EGFRCSF1RMAPK1TYK2MAPT | |
| SCHEMBL29544407 | 0.84 | CCNT1 (0.34) | EGFRCSF1RTYK2CCNT1CDK9 | |
| SCHEMBL29544781 | 0.84 | CCNT1 (0.34) | EGFRCSF1RTYK2CCNT1CDK9 | |
| SCHEMBL29544735 | 0.84 | CCNT1 (0.34) | EGFRTYK2CCNT1CDK9 | |
| SCHEMBL29544750 | 0.84 | EGFR (0.40) | EGFRCSF1RKDR | |
| SCHEMBL29544881 | 0.83 | ATM (0.38) | EGFRABCG2ATMPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |