Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 10/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544407 | 0.94 | CCNT1 (0.34) | CCNT1CDK9TYK2EGFRPARP1 | |
| SCHEMBL29544781 | 0.92 | CCNT1 (0.34) | CCNT1CDK9TYK2EGFRPARP1 | |
| SCHEMBL29545142 | 0.89 | CSF1R (0.39) | CCNT1CDK9TYK2EGFR | |
| SCHEMBL29544972 | 0.88 | EGFR (0.37) | CCNT1CDK9TYK2EGFRPARP1 | |
| SCHEMBL29545092 | 0.87 | EGFR (0.39) | CCNT1CDK9TYK2EGFR | |
| SCHEMBL29544955 | 0.86 | EGFR (0.39) | CCNT1CDK9TYK2EGFR | |
| SCHEMBL29544745 | 0.86 | TYK2 (0.36) | CDK9TYK2 | |
| SCHEMBL29544554 | 0.85 | BRD4 (0.38) | CCNT1CDK9TYK2EGFR | |
| SCHEMBL29544839 | 0.85 | TYK2 (0.34) | CCNT1CDK9TYK2EGFR | |
| SCHEMBL29544613 | 0.85 | EGFR (0.35) | CCNT1CDK9TYK2EGFRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |