SCHEMBL29544864

SCHEMBL29544864

O=C(O)c1ccc(-c2c3ccc4cc(O)ccc4c3oc3c2ccc2cc(=O)ccc23)c(C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 2/20 0.76
USP2 O75604 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
CA9 Q16790 4/20 0.40
MIF P14174 1/20 0.38
MAOA P21397 1/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
ATM Q13315 1/20 0.37
PLEC Q15149 1/20 0.37
PTPN1 P18031 1/20 0.37
DNASE1L3 Q13609 1/20 0.37
PRMT1 Q99873 1/20 0.37
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13180156 1.00 SOS1 (0.76) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL29543257 0.91 SOS1 (0.76) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL17312264 0.91 SOS1 (0.76) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL17254331 0.90 SOS1 (0.62) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL13015010 0.88 SOS1 (0.74) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL15277723 0.88 SOS1 (0.67) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL10059473 0.86 SOS1 (1.00) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL13180155 0.85 SOS1 (0.61) SOS1USP2L3MBTL1MEN1POLB
SCHEMBL13180154 0.83 SOS1 (0.59) SOS1USP2L3MBTL1CA9
SCHEMBL29546481 0.80 SOS1 (0.50) SOS1USP2L3MBTL1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
EP-4558646-A1 ENGINEERING DYNAMIC DNA NANO-DEVICES TO AMPLIFY SIGNAL President And Fellows Of Harvard College (US) 2025-05-28 EP disclosed
EP-4558647-A2 BARCODE DIFFUSION-BASED SPATIAL OMICS Digital Biology Inc. (US) 2025-05-28 EP disclosed
EP-4558819-A1 METHOD FOR HIGHLY MULTIPLEXED, THERMAL CONTROLLABLE DNA EXTENSION AND ITS APPLICATIONS President And Fellows Of Harvard College (US) 2025-05-28 EP disclosed
EP-4547759-A2 NOVEL FLUORESCENT DYES AND POLYMERS FROM DIHYDROPHENANTHRENE DERIVATIVES Beckman Coulter, Inc. (US) 2025-05-07 EP disclosed
WO-2025090968-A1 HYDROGEL CELL MIMICS WITH SUBCELLULAR FEATURES SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-01 WO disclosed
WO-2025075611-A1 ULTRASONIC INDICATOR BASED ON EMULSION FORMATION JP LABORATORIES, INC. (US) 2025-04-10 WO disclosed
WO-2025061922-A1 METHODS FOR SEQUENCING ILLUMINA, INC. (US) 2025-03-27 WO disclosed
EP-4499867-A2 TISSUE SPATIAL OMICS Digital Biology Inc. (US) 2025-02-05 EP disclosed
EP-4426357-A1 INTRACELLULAR DELIVERY COMPOSITIONS Biond Biologics Ltd. (IL) 2024-09-11 EP disclosed
WO-2023009529-A2 NOVEL POLYPEPTIDES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-02-02 WO disclosed
WO-2023288046-A1 COMPOSITIONS AND METHODS RELATING TO CELLS WITH ADHERED PARTICLES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-01-19 WO disclosed
WO-2022256229-A1 SYSTEMS AND METHODS FOR SEQUENCING NUCLEOTIDES USING TWO OPTICAL CHANNELS ILLUMINA CAMBRIDGE LIMITED (GB) 2022-12-08 WO disclosed
WO-2022251242-A1 COMPOSITIONS AND METHODS FOR MODIFYING DNA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-01 WO disclosed
WO-2022224257-A1 INTRACELLULAR DELIVERY COMPOSITIONS BIOND BIOLOGICS LTD. (IL) 2022-10-27 WO disclosed
EP-4073246-A1 COMPOSITIONS AND METHODS FOR LIGHT-DIRECTED BIOMOLECULAR BARCODING President And Fellows Of Harvard College (US) 2022-10-19 EP disclosed
CN-114989235-A Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis 哥伦比亚大学董事会 2022-09-02 CN disclosed
WO-2022150728-A1 NEUTRALIZING ANTIBODIES TO IL-17A, FUSION PROTEINS THEREOF, AND USES THEREOF LANIER BIOTHERAPEUTICS (US) 2022-07-14 WO disclosed
CN-108779138-B Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis 哥伦比亚大学董事会 2022-06-17 CN disclosed
EP-3997101-A1 NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-05-18 EP disclosed